Disease: Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
VAV1 P15498 vav guanine nucleotide exchange factor 1 1.00 0.556 0.769
TYK2 P29597 tyrosine kinase 2 Kinase 4.5E-08 0.505 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TFRC P02786 transferrin receptor Enzyme 7.0E-05 0.437 0.885
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
TET1 Q8NFU7 tet methylcytosine dioxygenase 1 1.00 0.523 0.808
TERT O14746 telomerase reverse transcriptase Enzyme 0.99 0.374 0.846
TBC1D9 Q6ZT07 TBC1 domain family member 9 Enzyme 2.8E-05 0.399 0.846
SUZ12 Q15022 SUZ12 polycomb repressive complex 2 subunit Nucleic acid binding 1.00 0.529 0.577
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
SETBP1 Q9Y6X0 SET binding protein 1 1.00 0.503 0.808
S100A8 P05109 S100 calcium binding protein A8 Calcium-binding protein 0.14 0.430 0.962
S100A4 P26447 S100 calcium binding protein A4 Calcium-binding protein 6.2E-03 0.448 0.769
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
RPS6KA3 P51812 ribosomal protein S6 kinase A3 Kinase 1.00 0.491 0.846
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
RASA1 P20936 RAS p21 protein activator 1 Enzyme modulator 1.00 0.481 0.885
RAC1 P63000 Rac family small GTPase 1 Enzyme modulator 0.76 0.429 0.962
PTPRC P08575 protein tyrosine phosphatase receptor type C Enzyme 1.00 0.435 0.808
PTPN6 P29350 protein tyrosine phosphatase non-receptor type 6 1.00 0.485 0.769